Abstract: The influences of the environment on railway transportation safety on Gulmud-Lasa line in Qinghai-Tibet railway was analyzed, the necessity of a transportation safety supervision information system for the railway line was discussed. The initial design of the system was presented. In the design, the environment and facility arrangement along this railway are taken into consideration. Computernetwork technique andmodern equipmentare used to continuouslymonitor the environments and the operation status of the facilities. All distributed monitoring systems along the railway line are connected with the safety monitor center, realizing central management and share of information collected along the line.