磁悬浮人工心脏泵及其在体外循环系统上的试验研究

刘淑琴; 边忠国; 李瑞建; 刘凯; 林本涛; 赵思鹏; 宗清会

doi:10.3969/j.issn.0258-2724.20211012

磁悬浮人工心脏泵及其在体外循环系统上的试验研究

doi: 10.3969/j.issn.0258-2724.20211012

1.
山东大学电气工程学院，山东济南 250061
2.
山东大学齐鲁医院，山东济南 250012
3.
山东管理学院智能工程学院，山东济南 250357

基金项目: 国家重点研发计划（2020YFC1512703）

详细信息

作者简介:
刘淑琴（1958—），女，教授，研究方向为磁悬浮理论与应用，E-mail：lshuqin@sdu.edu.cn

中图分类号: TH311；TH77
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- 被引次数: 0
出版历程
- 收稿日期: 2021-12-08
- 修回日期: 2022-04-21
- 网络出版日期: 2023-06-19
- 刊出日期: 2022-04-27

Maglev Artificial Heart Pump and Experimental Study on ECMO

1.
School of Electrical Engineering, Shandong University, Jinan 250061, China
2.
Qilu Hospital, Shandong University, Jinan 250012, China
3.
School of Intelligent Engineering, Shandong Management University, Jinan 250357, China

摘要

摘要:
体外循环生命支持系统（extracorporeal membrane oxygenation，ECMO）可替代人的心、肺工作，为挽救生命创造机会，在这次抗击新冠疫情中屡建奇功，被称为“救命神器”. 针对作为ECMO动力源的磁悬浮人工心脏泵，本文对其磁悬浮系统和无接触高效率磁耦合驱动装置进行了研究；在多入多出智能控制系统控制下实现了磁悬浮人工心脏泵变速稳定运行，并开展了磁悬浮人工心脏泵的压力、流量和转速实验；用所研制的磁悬浮人工心脏泵进行了3 d的动物实验后自主撤机. 研究结果表明：体外循环磁悬浮离心血泵表现出良好的稳定运行特性，保持转速不变，在流量变化较大时，进出口压力差变化不大；体外循环磁悬浮离心血泵在转速为5000 r/min时，进出口压力差可以达到750 mmHg，具有较宽的工况范围；持续进行了15 d可靠性试验后，各项测试参数符合特性曲线规律；试验期间，羊生命体征持续存在，撤机后羊的生命体征平稳，验证了所研发的磁悬浮人工心脏泵在ECMO系统上应用的有效性和安全性.
- 磁悬浮 /
- 人工心脏泵 /
- 磁耦合 /
- ECMO
Abstract:
Extracorporeal membrane oxygenation (ECMO) can replace human heart and lung work and create opportunities to save lives. ECMO has made outstanding achievements in defending against the novel coronavirus pneumonia and has thus been called a lifesaving appliance. In view of the power source of ECMO, namely the maglev artificial heart pump, its maglev system and contactless high-efficiency magnetic coupling driver were studied. The maglev artificial heart pump was controlled by a multi-input and multi-output intelligent control system to realize variable speed and stable operation. The experiments of pressure, flow, and speed of the maglev artificial heart pump were carried out. The developed maglev artificial heart pump was used for three days of animal experiments and active withdrawal. The results show that the extracorporeal maglev centrifugal pump shows excellent stable operation characteristics and keeps the speed unchanged; the pressure difference between the inlet and outlet does not change much when the flow rate varies greatly. The pressure difference between the inlet and outlet of the extracorporeal maglev centrifugal pump can reach 750 mmHg at a speed of 5 000 r/min, which has a wide working range. After 15 days of continuous reliability experiments, all test parameters conform to the law of characteristic curves. During the test, the vital signs of the sheep were monitored and were stable after the machine was removed, which verified the effectiveness and safety of the developed maglev artificial heart pump applied in ECMO.
- maglev /
- artificial heart pump /
- magnetic coupling /
- ECMO

HTML全文

图 1 单端轴向分离式磁轴承

Figure 1. Single-ended axial separable magnetic bearing

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图 2 轴向永磁斥力轴承

Figure 2. Axial permanent magnet repulsion bearing

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图 3 分散型磁耦合驱动

Figure 3. Decentralized magnetic coupling drive

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图 4 相位角示意

Figure 4. Phase angle

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图 5 磁力线分布

Figure 5. Distribution of magnetic lines

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图 6 整体转矩与相位角的关系

Figure 6. Relationship between total torque T and phase angle

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图 7 第三代磁悬浮人工心脏泵

Figure 7. Third-generation maglev artificial heart pump

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图 8 控制系统框图

Figure 8. Control system

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图 9 人工心脏泵的支撑臂

Figure 9. Support arm for artificial heart pump

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图 10 手摇驱动装置

Figure 10. Handheld driver artificial heart pump

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图 11 ECMO样机

Figure 11. ECMO prototype

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图 12 闭式体外循环模拟系统

Figure 12. Closed extracorporeal circulation simulation system

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图 13 Q-P曲线

Figure 13. Q-P curves

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图 14 ECMO样机的动物实验

Figure 14. Animal experiment with ECMO prototype

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表 1 钕铁硼N52参数

Table 1. Parameters of neodymium iron boron N52

规格剩磁/T 矫顽力/
（ kA·m⁻¹）内禀矫顽力/
（ kA·m⁻¹）最大剩磁积/
（kJ·m⁻³）工作温度/℃

N52 1.42～
1.49 ≥835 ≥876 390～422 ≤80

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参考文献(22)

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规格	剩磁/T	矫顽力/ （ kA·m⁻¹）	内禀矫顽力/ （ kA·m⁻¹）	最大剩磁积/ （kJ·m⁻³）	工作温度/℃
N52	1.42～ 1.49	≥835	≥876	390～422	≤80

磁悬浮人工心脏泵及其在体外循环系统上的试验研究

doi: 10.3969/j.issn.0258-2724.20211012

作者简介: 刘淑琴（1958—），女，教授，研究方向为磁悬浮理论与应用，E-mail：lshuqin@sdu.edu.cn

计量

出版历程

Maglev Artificial Heart Pump and Experimental Study on ECMO

计量

出版历程

目录

作者简介:
刘淑琴（1958—），女，教授，研究方向为磁悬浮理论与应用，E-mail：lshuqin@sdu.edu.cn