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影响猪胰管封闭效果的电刀参数分析

郑靖 刘祎程 张浩 杨丹 李可洲

郑靖, 刘祎程, 张浩, 杨丹, 李可洲. 影响猪胰管封闭效果的电刀参数分析[J]. 西南交通大学学报, 2022, 57(2): 245-252. doi: 10.3969/j.issn.0258-2724.20200391
引用本文: 郑靖, 刘祎程, 张浩, 杨丹, 李可洲. 影响猪胰管封闭效果的电刀参数分析[J]. 西南交通大学学报, 2022, 57(2): 245-252. doi: 10.3969/j.issn.0258-2724.20200391
ZHENG Jing, LIU Yicheng, ZHANG Hao, YANG Dan, LI Kezhou. Analysis of Electrosurgical Unit Parameters on Sealing Effect of Porcine Pancreatic Duct[J]. Journal of Southwest Jiaotong University, 2022, 57(2): 245-252. doi: 10.3969/j.issn.0258-2724.20200391
Citation: ZHENG Jing, LIU Yicheng, ZHANG Hao, YANG Dan, LI Kezhou. Analysis of Electrosurgical Unit Parameters on Sealing Effect of Porcine Pancreatic Duct[J]. Journal of Southwest Jiaotong University, 2022, 57(2): 245-252. doi: 10.3969/j.issn.0258-2724.20200391

影响猪胰管封闭效果的电刀参数分析

doi: 10.3969/j.issn.0258-2724.20200391
基金项目: 国家自然科学基金(51675356)
详细信息
    通讯作者:

    郑靖(1974—),女,研究员,研究方向为生物摩擦学与表面工程,E-mail:zhengj168@163.com

  • 中图分类号: R657.5;R332

Analysis of Electrosurgical Unit Parameters on Sealing Effect of Porcine Pancreatic Duct

  • 摘要:

    高频电刀的组织热效应可以使胰腺组织表面生成焦痂,具有止血防胰瘘的效果. 高频电刀机电参数对焦痂止血防胰瘘功能具有显著影响,但尚缺乏对其作用规律的深入研究. 采用体外模拟试验方法,结合胰管爆破压测试和焦痂形貌研究了干燥模式下3种关键机电参数(电刀功率、作用时间和电极前端直径)对胰管封闭效果的影响规律;基于此,采用响应面分析法获取电刀功率、作用时间和电极前端直径之间的交互作用关系以及具有最佳胰管封闭效果的机电参数. 研究结果表明:单一变量下,电刀功率为60 W时胰管爆破压处于峰值,作用时间为2.00 s时胰管爆破压处于峰值,电极前端直径为2.00 mm时胰管爆破压处于峰值;干燥模式下的最佳机电参数为电刀功率59.39 W、作用时间2.18 s、电极前端直径2.31 mm;此外,电极前端直径是影响胰管封闭效果的独立因素,电刀功率和作用时间有显著性的交互作用,共同影响胰管封闭效果.

     

  • 图 1  爆破压测试装置和高频电刀装置

    Figure 1.  Burst pressure test device and electrosurgical unit

    图 2  不同作用功率作用下的猪胰管爆破压

    Figure 2.  Burst pressure of porcine pancreatic duct under different power

    图 3  不同作用时间下猪胰管爆破压

    Figure 3.  Burst pressure of porcine pancreatic duct under different action time

    图 4  不同直径电极作用下猪胰管爆破压

    Figure 4.  Burst pressure of porcine pancreatic duct under different diameter electrodes

    图 5  焦痂表面LCSM形貌

    Figure 5.  LCSM morphology of eschar surface

    图 6  焦痂剖面OM形貌

    Figure 6.  OM morphology of eschar section

    图 7  残差正态概率

    Figure 7.  Residual normal probability

    图 8  方程模型的拟合度

    Figure 8.  Goodness-of-fit of empirical model

    图 9  不同作用功率和作用时间下爆破压等高线与响应曲面

    Figure 9.  Contour plots and Response surface of burst pressure under different power and times

    图 10  不同电极前端直径和作用功率下爆破压等高线与响应曲面

    Figure 10.  Contour plots and Response surface of burst pressure under different electrode diameter and power

    图 11  不同电极前端直径和作用时间下爆破压等高线与响应曲面

    Figure 11.  Contour plots and response surface of burst pressure under different electrode diameter and times

    图 12  最佳机电参数作用下焦痂形貌

    Figure 12.  Morphology of eschar under the best electro-mechanical parameters

    表  1  响应面试验设计因素水平表

    Table  1.   Levels of independent variables for BBD

    因素水平
    −101
    高频电刀功率/W506070
    作用时间/s1.002.003.00
    电极前端直径/mm1.002.003.00
    下载: 导出CSV

    表  2  响应面试验点与试验结果

    Table  2.   Test points and results of BBD

    试验号作用
    功率/W
    作用
    时间/s
    电极
    直径/mm
    胰管爆
    破压/kPa
    1 50 2.00 3.00 5.65
    2 50 3.00 2.00 6.85
    3 60 2.00 2.00 8.95
    4 70 2.00 1.00 3.83
    5 60 2.00 2.00 9.04
    6 70 2.00 3.00 6.56
    7 70 1.00 2.00 4.75
    8 50 2.00 1.00 5.36
    9 60 3.00 1.00 4.55
    10 60 1.00 3.00 5.75
    11 50 1.00 2.00 3.85
    12 60 1.00 1.00 4.23
    13 60 2.00 2.00 9.47
    14 60 3.00 3.00 7.69
    15 60 2.00 2.00 9.62
    16 70 3.00 2.00 4.17
    17 60 2.00 2.00 9.18
    下载: 导出CSV

    表  3  爆破压响应面回归模型方差分析

    Table  3.   ANOVA test results for burst pressure model

    方差来源离差平方和自由度均方差F 检验值P 显著性
    模型 73.006 9 8.112 67.95 < 0.001 **
    A 0.723 1 0.723 6.06 0.043 *
    B 2.735 1 2.735 22.92 0.002 *
    C 7.367 1 7.367 61.71 < 0.001 **
    AB 3.188 1 3.188 26.71 0.001 *
    AC 1.484 1 1.484 12.43 0.010 *
    BC 0.663 1 0.663 5.56 0.051
    A2 21.797 1 21.797 182.59 < 0.001 **
    B2 18.033 1 18.033 151.06 < 0.001 **
    C2 11.170 1 11.170 93.57 < 0.001 **
    残差 0.836 7 0.119
    失拟性 0.508 3 0.169 2.070 0.247 不显著
    标准差 0.346 复相关系数 0.988
    平均数 6.440 校正复相关系数 0.974
    变异系数/% 5.365 预测复相关系数 0.883
    预测残差平方和 8.642 信噪比 21.786
    注:**为极显著,*为显著.
    下载: 导出CSV
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出版历程
  • 收稿日期:  2020-06-24
  • 修回日期:  2021-03-03
  • 网络出版日期:  2021-03-08
  • 刊出日期:  2021-03-08

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