Abstract: This study investigates static wind and buffeting responses of long-span suspension bridges under non-stationary winds in the mountainous area, where a suspension bridge located in Yunnan province was taken as an example. Firstly, a scheme to reasonably determine the mean wind speed and accurately estimate the power spectrum density of wind fluctuation based on measured wind samples at the bridge site was introduced. Then, the nonlinear static wind response was calculated by considering the initial internal force state under dead load. Finally, based on the measured wind spectrum and the specification spectrum that is derived from the bridge design code, buffeting responses of the bridge were analyzed by the pseudo excitation method. The results show that the displacement of girder is dominated by the vertical vibration, and the dynamic displacement is larger than its static counterpart significantly. In addition, the static displacement is underestimated if an interval of 10 min is used to derive the mean wind speed; the wind spectrum based on the specification wind spectrum may lead to underestimated girder buffeting response,and threaten the bridge safety. These findings can provide useful references for the static and buffeting analyses of other long-span bridges constructed in mountainous terrains.