Abstract: In order to avoid the disadvantages of the existing design methods for multi-frame beams with anchor bolts used to stabilize high soft-rock slopes, a novel design method was proposed on the basis of interaction mechanism between a structure and a slope. With the proposed method, tensile forces of anchor bolts are determined by analyzing slope stability in terms of design safety factor and failure mode of a slope, and then internal forces of frame beams are calculated from static equilibrium and deformation compatibility conditions between anchor bolts and frame beams and the Winkler foundation model used to interpret interaction between frame beams and a slope. The method was verified by a laboratory model test. The research results show that the distribution mode of slope pressure on every frame beam is a parabola in the direction of the longitudinal axis.