Abstract: In order to probe into factors influencing the wind-rain-induced vibration of cables in cable-stayed bridges, a systemic parametric investigation was carried out based on the modified galloping model and aerodynamic coefficients from spatial model tests. They are aerodynamic parameters, including rivulet shape, yaw angle, cable diameter and so on, motion parameters such as initial cable condition, rivulet motion and so on, and structural parameters, including the frequency, damping and mass of cable. The research results show that the aerodynamic parameters and the motion parameters will affect the maximum amplitude response of cable wind-rain-induced vibration and change the range of wind speed resulting in the rain-wind-induced vibration.