植入式生物燃料电池的体外实验

林洁琼; 周晓勤; 马龙

植入式生物燃料电池的体外实验

林洁琼^1,2,
周晓勤^2, ,,
马龙^2,3

基金项目:

吉林省科技支撑计划社会发展重点资助项目(20070419)

详细信息

作者简介:
林洁琼(1969- ),女,副教授,博士,电话:0431-85716615,E-mail:linjieqiong@mail.ccut.edu.cn

通讯作者:
周晓勤(1967- ),男,教授,博士,研究方向为生物燃料电池,电话: 0431-85683001, E-mail: xqzhou@jlu.edu.cn

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出版历程
- 收稿日期: 2009-04-23

Experiments in Vitro of Biofuel Cell for Implantable Medical Devices

LIN Jieqiong^1,2,
ZHOU Xiaoqin^{2
, ,},
MA Long^2,3

摘要

摘要: 开发了一种利用生理体液的植入式生物燃料电池(BFC)原型装置.通过模拟人体生理环境,进行了植入式生物燃料电池的体外试验.讨论了葡萄糖反应液的浓度、温度和pH值对生物燃料电池输出电流的影响,实验结果表明:随着葡萄糖反应液浓度的降低,生物燃料电池的输出电流相应减少,持续供电时间缩短;随着反应液pH值的降低,生物燃料电池的输出电流增大;升高反应液温度会使生物燃料电池的输出电流产生振荡.
- 植入式医疗装置 /
- 生物燃料电池 /
- 体外实验 /
- 电极修饰
Abstract: A prototype device of an implantable biofuel cell(BFC) that utilizes body fluid was developed,and experiments in vitro were carried out for the implantable BFC in a simulated physiological environment of human body,to investigate the influences of the concentration,temperature,and pH value of glucose solution on the electric current output of the BFC prototype device.The experimental results show that as the concentration of glucose solution decreased,the electric current output of the BFC decreased,and the sustaining time of power supply of the BFC shortened.On the other hand,the electric current increased with the decrease of the pH value of the glucose solution.Lifting the temperature of the reaction solution would cause oscillation to occur to the current output of the BFC.
- implantable medical device /
- biological fuel cell /
- experiments in vitro /
- electrode modification

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参考文献(1)

HELLER A.Potentially implantable miniature batteries[J].Anal.Bioanal.Chem.,2006,385(3):469-473.[2] JUSTIN G A.Biofuel cells as a possible power source for implantable electronic devices[D].Pittsburgh:University of Pittsburgh,2004.[3] BARTON S C,GALLAWAY J,ATANASSOV P.Enzymatic biofuel cells for implantable and microscale devices[J].Chem.Rev.,2004,104(10):4867-4886.[4] MANO N,MAO F,HELLER A.A miniature membrane-less biofuel cell operating at +0.60 V under physiological conditions[J].ChemBioChem,2004,5(12):1703-1705.[5] SATO F,TOGO M,ISLAM M K,et al.Enzyme-based glucose fuel cell using vitamin K3-immobilized polymer as an electron mediator[J].Electrochemistry Communications,2005,7(7):643-647.[6] WILLNER I,YAN Y M,WILLNER B,et al.Integrated enzyme-based biofuel cells-a review[J].Fuel Cells,2009,9(1):7-24.[7] CHEN T,BARTON S C,BINYAMIN G,et al.A miniature biofuel cell[J].J.Am.Chem.Soc.,2001,123(35):8630-8631.[8] LATHAM R,LINFORD R,SCHLINDWEIN W.Biomedical applications of batteries[J].Solid State Ionics,2004,172(1-4):7-11.[9] YUHASHI N,TOMIYAMA M,OKUDA J,et al.Development of a novel glucose enzyme fuel cell system employing protein engineered PQQ glucose dehydrogenase[J].Biosensors and Bioelectronics,2005,20(10):2145-2150.[10] CHIAO M,LIN L,LAM K.Implantable,miniaturized microbial fuel cell:United States,7160637[P].2007.

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文章访问数: 1557
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