Abstract: Large buildings were classified according to their functions.A sensitivity analysis index system for traffic impact of large building on traffic of road networks was established using analytic hierarchy process,and the models for calculating the indices were derived based on the principles of traffic engineering and system engineering.The uncertain factors in the main sensitivity analysis indices of traffic impact were determined.The traffic impacts before and after changes in uncertainty factors were correlated.The method for sensitivity analysis of traffic impact on large buildings on traffic of road network was proposed.and gave The Nan’an Sports Center in Chongqing was taken as an example,and the results show that the variation rate is the main sensitivity index.