心肌肥大病理图像的计算机分析方法
AnalysisM ethod forM yocardium Hypertrophy Images
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摘要: 为提高心肌肥大病理图像量化评估的效率,提出了基于Hough变换的计算机分析方法.首先对心肌纵切 切片图像进行Hough变换,检测出心肌纤维走向.然后采集与心肌纤维走向相垂直方向上的灰度分布信息,用迭 代阈值法分割出肌纤维区域与肌纤维间隙区域,测量肌纤维直径.t检验分析表明,用该方法得到的心肌纤维数 目和平均尺寸与人工测量结果一致(P>0. 05).Abstract: To increase the efficiency for measuring the size ofmyocardium fibers in evaluation of myocardium hypertrophy, an analysismethod formyocardium hypertrophy imageswas proposed based onHough transform. W ith thismethod, Hough transform is performed on the image ofmyocardium fibers to detected the direction of the fibers. Lines perpendicular to the fiber direction are generated, on which the distribution of gray levels are collected. The lines are divided into low gray levels representing fiberwidths and high gray levels reprensenting the gaps between the fibers. In thisway, the numberand the averagewidth of fibers aremeasured. Thettestresults (P>0. 05) show thatthere is no significantdifference between the resultsmeasuredwith the proposedmethod and by hands.
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Key words:
- myocardium hypertrophy /
- myocardium fiber /
- image analysis /
- Hough transform /
- measurement
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