• ISSN 0258-2724
  • CN 51-1277/U
  • EI Compendex
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Volume 22 Issue 4
Aug.  2009
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Article Contents
LIN Jieqiong, ZHOU Xiaoqin, MA Long. Experiments in Vitro of Biofuel Cell for Implantable Medical Devices[J]. Journal of Southwest Jiaotong University, 2009, 22(4): 600-603,619.
Citation: LIN Jieqiong, ZHOU Xiaoqin, MA Long. Experiments in Vitro of Biofuel Cell for Implantable Medical Devices[J]. Journal of Southwest Jiaotong University, 2009, 22(4): 600-603,619.

Experiments in Vitro of Biofuel Cell for Implantable Medical Devices

  • Received Date: 23 Apr 2009
  • A prototype device of an implantable biofuel cell(BFC) that utilizes body fluid was developed,and experiments in vitro were carried out for the implantable BFC in a simulated physiological environment of human body,to investigate the influences of the concentration,temperature,and pH value of glucose solution on the electric current output of the BFC prototype device.The experimental results show that as the concentration of glucose solution decreased,the electric current output of the BFC decreased,and the sustaining time of power supply of the BFC shortened.On the other hand,the electric current increased with the decrease of the pH value of the glucose solution.Lifting the temperature of the reaction solution would cause oscillation to occur to the current output of the BFC.

     

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  • HELLER A.Potentially implantable miniature batteries[J].Anal.Bioanal.Chem.,2006,385(3):469-473.[2] JUSTIN G A.Biofuel cells as a possible power source for implantable electronic devices[D].Pittsburgh:University of Pittsburgh,2004.[3] BARTON S C,GALLAWAY J,ATANASSOV P.Enzymatic biofuel cells for implantable and microscale devices[J].Chem.Rev.,2004,104(10):4867-4886.[4] MANO N,MAO F,HELLER A.A miniature membrane-less biofuel cell operating at +0.60 V under physiological conditions[J].ChemBioChem,2004,5(12):1703-1705.[5] SATO F,TOGO M,ISLAM M K,et al.Enzyme-based glucose fuel cell using vitamin K3-immobilized polymer as an electron mediator[J].Electrochemistry Communications,2005,7(7):643-647.[6] WILLNER I,YAN Y M,WILLNER B,et al.Integrated enzyme-based biofuel cells-a review[J].Fuel Cells,2009,9(1):7-24.[7] CHEN T,BARTON S C,BINYAMIN G,et al.A miniature biofuel cell[J].J.Am.Chem.Soc.,2001,123(35):8630-8631.[8] LATHAM R,LINFORD R,SCHLINDWEIN W.Biomedical applications of batteries[J].Solid State Ionics,2004,172(1-4):7-11.[9] YUHASHI N,TOMIYAMA M,OKUDA J,et al.Development of a novel glucose enzyme fuel cell system employing protein engineered PQQ glucose dehydrogenase[J].Biosensors and Bioelectronics,2005,20(10):2145-2150.[10] CHIAO M,LIN L,LAM K.Implantable,miniaturized microbial fuel cell:United States,7160637[P].2007.
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