In order to investigate the route hotspot problem in wireless sensor network (WSN), a BS- CH (base station-cluster head) hybrid mobile strategy based on event-driven, BS-CH HMS (base station-cluster head hybrid mobile strategy), was proposed on the assumption of CH mobility. In this strategy, the mobile path of CH (cluster head) is determined and the cooperative mobile strategy of the base station is designed in light of the energy consumption of moving CH. The theoretical analysis and simulation results show that using the BS-CH HMS compared with using a single CH mobile strategy, CH energy consumption is decreased by 30% to enhance the energy efficiency of moving CH and prolong the lifetime of WSN.